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Specification:100ul/200ul/1mlDescription :
Retinoblastoma binding protein 6 The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds…
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Specification:100ul/200ul/1ml Description:
NRP2 is a member of the neuropilin family of receptor proteins. This transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin…
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Description:
Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine.
Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the…
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Description:
Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to…
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Description:
Osterix is a C2H2 zinc finger transcription factor of the SP gene family and is a putative "master" regulator of bone cell differentiation (Gao et al., 2004). It is essential for osteoblast differentiation and binds to Sp1 and EKLF consensus sequences and to other G/C-rich sequences. The Sp7 knockout phenotype is similar to that of…
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Specification:100ul/200ul/1ml Description:
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus…
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Specification:100ul/200ul/1ml Description:
Osteoprotegerin (OPG) is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular…
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Specification:100ul/200ul/1mlDescription:
Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene.Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder.
Factor VIII participates in blood coagulation; it is a…