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Specification:100ul/200ul/1ml Description:
The ING1 gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a component of the p53 signalling pathway and is a nuclear protein that physically interacts with the tumor suppressor protein TP53. Rearrangement and reduced expression of this gene…
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Specification:100ul/200ul/1ml Description:
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions…
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Specification:100ul/200ul/1ml Description:
IRAK2 encodes the Interleukin 1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the Interleukin 1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NFkappaB.
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Specification:100ul/200ul/1ml Description:
IRS P53 (Insulin receptor substrate protein of 53 kDa) is an adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. IRS P53 is necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. It is involved in the…
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Specification:100ul/200ul/1ml Description:
Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling…
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Specification:100ul/200ul/1ml Description:
Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a…
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Specification:100ul/200ul/1ml Description:
Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic…
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Specification:100ul/200ul/1ml Description:
The IGF2 gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is expressed only from the paternally inherited allele and is an imprinted gene which is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns…