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Specification:100ul/200ul/1mlDescription:
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to…
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Description:
Nociceptin (Orphanin FQ, OFQ), a heptadecapeptide peptide, has been designated as an endogenous ligand for the ORL1 receptor. The amino acid sequence of nociceptin hashomology with other opioid peptides, especially the prodynorphin fragment dynorphin A, suggesting a close evolutionary relationship between the precursors. A diffuse…
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Specification:100ul/200ul/1mlDescription:
The nociceptin receptor (KOR-3) is the receptor for the neuropeptide nocipeptin/orphanin FQ. KOR-3 has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions . The KOR-3 activity is mediated by G proteins which inhibit adenyl cyclase.
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Description:
Nogo Receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. It is also a receptor for Nogo A (RTN4), OMG and MAG.
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Description:
NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Re ticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE (reviewed in 1). NogoA was initially…
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Specification:100ul/200ul/1mlDescription:
Nogo-B is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multidomain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal…
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Specification:100ul/200ul/1mlDescription:
Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The…
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Description:
Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene.
COX-1 promotes the production of the natural mucus lining that protects the inner stomach and contribute to reduced acid secretion and…