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Description:
Mitochondrial fusion may regulate mitochondrial morphogenesis and underlie complementation between mitochondrial genomes in mammalian cells. Mitochondrial dysfunction is a major cause of neuronal death in degenerative disorders, such as Parkinson’s disease, and can be triggered by an imbalance in the dynamic equilibrium between…
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Specification:100ul/200ul/1mlDescription:
NK1, a member of the NKRPI family of cell surface receptors, is a type II integral membrane protein with a C type lectin domain. It is expressed as a disulfide linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice. NK1 mediates cellular…
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Specification:100ul/200ul/1mlDescription:
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene…
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Specification:100ul/200ul/1mlDescription:
There are three known mammalian tachykinin receptors termed NK1, NK2 and NK3. All are members of the 7 transmembrane g protein-coupled family of receptors and induce the activation of phospholipase C, producing inositol triphosphate. NK1, NK2 and NK3 selectively bind to substance P, neurokinin A and…
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Specification:100ul/200ul/1mlDescription:
Type III Collagen is found co-localized with Type I Collagen in tissues, blood vessels and skin. Type III Collagen is a homotrimeric procollagen comprised of three identical pro a, (III) chains.1 Collagen III is important for the development of skin and the cardiovascular system and for maintaining normal…
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Description:
Collagen type IV is a major component of basement membranes, such as those associated with capillaries and within glomeruli. It is composed of α1(IV) chain and α2(IV) chain in 2:1 ratio. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can…
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Specification:100ul/200ul/1mlDescription:
Collagen type VI shows a high affinity, specific interaction with biglycan and decorin by binding with high affinity to its core protein. The interaction is with the N-terminal globular domain of the collagen 6. as well as interactions with other matrix proteins e.g. hyaluronan, heparan sulphate and NG-2…
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Specification:100ul/200ul/1mlDescription:
Type-I collagen is the most abundant collagen of the human body.
It is present in scar tissue, the end product when tissue heals by repair.
It is found in tendons, the endomysium of myofibrils and the organic part of bone.