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Specification:96testDescription:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive…
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Description:
Matrix metallopeptidase 12 (macrophage elastase), also known as MMP12, is a human gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such…
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Specification:96testDescription:
MMP-13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis . In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. MMP-13 is likely to play…
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Specification:96testDescription:
Laminins are the major non-collagenous component of the basal lamina, such as those on which cells of an epithelium sit.They are a family of glycoproteins that are an integral part of the structural scaffolding of basement membranes in almost every animal tissue. Laminins are secreted and incorporated into cell-…
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Specification:96testDescription:
Stem cell factor / KIT ligand (SCF) (MGF)is a cytokine which binds CD117 (c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth…
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Specification:96testDescription:
MIP-1(macrophage inflammatory protein-1) is an acidic protein. MIP- 1α and MIP-1β have a length of 69 amino acids (7.8 kDa). The two MIP proteins are the major factors produced by macrophages following their stimulation with bacterial endotoxins. Both proteins are involved in the cell
activation of human…
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Description:
Midkine (MK, also called neurite growth promoting factor 2, NEGF-2), a product of a retinoic acid responsive gene, is a secreted 13 kDa protein belonging to the family of heparin binding growth/differentiation factors. MK shares 45% sequence identity with other member of this family called Pleiotrophin (HB-GAM). Midkine is composed…
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Specification:96testDescription:
MIG (monokine induced by gamma-interferon) also called MIG-1. Human MIG has a length of 103 amino acids (11.7 kDa). The protein belongs to the family of chemotactic cytokines known as Chemokines (CXCchemokines). The human MIG gene has been localized to chromosome 4q21 in the immediate vicinity (less than 16 kb) of…
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Description:
The human CXCL9 Kit is a sandwich ELISA. The capture antibody is a polyclonal human CXCL9 antibody pre-coated onto the 96-well strip plates provided in the kit. Human test samples and standards of known CXCL9 concentration are added to these wells and allowed to complex with the bound CXCL9 antibody. A biotinylated human CXCL9…
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Description:
Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins.They activate…