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Specification:96testDescription:
Tryptase(TPS) is the most abundant secretory granule-derived serine proteinase contained in mast cells that has recently been used as a marker for mast cell activation. It is involved with allergenic response and is suspected to act as a mitogen for fibroblast lines. Elevated levels of serum tryptase occur in both…
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Specification:96testDescription:
TSH receptor autoantibodies (TRAb) - These autoantibodies are responsible for a common form of thyroid overactivity known as Graves' disease and in this condition the antibodies bind to the receptor for thyroid stimulating hormone (TSH) and mimic the effects of TSH in an uncontrolled way. Clinically, the…
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Specification:96testDescription:
Type I plasminogen activator inhibitor (PAI-1) is a 43 kDa serpin family member that inhibits tissue- and urokinase-type plasminogen activators (t-PA, u-PA). This protein appears to be an important regulator of plasminogen activation by t-PA and extracellular proteolysis by u-PA. The plasminogen activator…
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Specification:96testDescription:
Proteinase-3 is a lysosomal enzyme that can be found in human neutrophils. There are two subsets of autoantibody to human neutrophils: c- ANCA and p-ANCA. The first subtype, c-ANCA, shows cytoplasmic staining by IFA and is diagnostic for Wegener's granulomatosis. The major antigen responsible for the c-ANCA…
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Specification:96testDescription:
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils monocytes and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal…
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Specification:96testDescription:
MCP 5 Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate assays.
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Specification:96testDescription:
M-CSF, also known as CSF-1, can be either expressed on the cell surface as a membrane-spanning 68-86 kDa chondroitin or secreted as an 80-100 kDa glycoprotein or 130-160 kDa chondroitin sulfate-containing proteoglycan. The biologically active forms of M-CSF are dimeric. The following tissues are known producers…
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Specification:96testDescription:
Macrophage-derived Chemokine (MDC) is a CC chemokine that is a potent chemoattractant for dendritic cells, natural killer cells, and the Th2 subset of peripheral blood T lymphocytes . In addition, MDC has also been shown to possess anti-HIV-1 activity . Expression of MDC mRNA has been identified in macrophages…
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Specification:96testDescription:
Monocyte chemotactic protein-2 (MCP-2) is found in the conditioned medium of human osteosarcoma cell line MG-63 that also secretes some other chemotactic factors including IL-8 and MCP-1. MCP-2 is related closely to MCP-1 and MCP-3. MCP-2 is a member of the family of CCChemokines and specifically attracts monocytes…
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Specification:96testDescription:
Monocyte chemoattractant protein-1 (MCP-1) called also monocyte chemotactic protein-1. MCP-1 belongs to the family of chemotactic cytokines known as Chemokines. MCP-1 is expressed by monocytes, vascular endothelial cells, smooth muscle cells, glomerular mesangial cell, osteoblastic cells, and human pulmonary type-2…