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Description:
The biological functions of IL-12 are mediated through specific receptors on T and NK cells. To date, two IL-12 receptor subunits have been identified in mouse and humans. These receptor subunits are members of the cytokine receptor superfamily. Their cytoplasmic regions contain the box1 and box2 motifs that exist in other cytokine…
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Description:
Interleukin-13 (IL-13) was first described as a protein product, designated P600, encoded by an RNA produced by activated mouse Th2 cells . More recently, the cDNA cloning of the human homologue of P600, human IL-13, has been reported . Human IL-13 is a nonglycosylated protein of 132 amino acids with a molecular weight of 12000Da. The…
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Description:
IL-13 is an immunoregulatory cytokine secreted predominantly by acvated T cells that exerts its effects mainly on B cells and monocytes.In B cells, IL-13 enhances survival and proliferation, and stimulates immunoglobulin heavy chain class switching to IgE and IgG4.
IL-13 is a key mediator of allergic inflammation and has been…
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Description:
Human IL-22 ELISA kit contains all the necessary reagents required for performing quantitative measurement of Human IL-22 levels from samples including serum, plasma, culture medium or other biological fluids in a sandwich ELISA format.
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Description:
IL-15 (Interleukin-15) is found in conditioned medium of a monkey kidney epithelial cell line, CV-1/EBNA. It is a glycoprotein of 14-15 kDa.
Human IL-15 has been cloned from a human stromal cell line, IMTLH. Stromal cell line IL-15 has been shown to be produced by human fetal astrocytes and microglia in response to IL-1β or IFN-γ and…
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Description:
Interleukin 21 (IL-21), is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. IL-21 elicits its effects on immune cells by…
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Description:Assay Range:20-3200 pg/ml Detection Target:IL-16 Quantity:1 x 96 Sample Type:Sensitivity:<20 pg/ml
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Description:
Interleukin 17 (IL-17; also known as IL-17A) is a 30 - 35 kDa variably glycosylated homodimeric protein that belongs to a unique family of cysteine-knot related proteins. Its sequence was originally isolated from an activated rodent hybridoma and termed CTLA-8 . It is synthesized as a 155 amino acid (aa) precursor that contains a 23…
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Description:
Interleukin 18 (IL-18) is a 18 kDa novel cytokine which is identified as a costimulatory factor for production of interferon-γ (IFN- γ ) in response to toxic shock. It shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24 kDa molecule without a signal peptide and must be cleaved to produce an active…
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Description:
IL-18 binding protein (IL-18BP) is a circulating antagonist of the proinflammatory Th1 cytokine IL-18.
IL-18BP belongs to a growing family of soluble inding proteins (osteoprotegerin and cytokine-like actor-1), which are not variants of their cell bound eceptors. Its major splice variant IL-18BPa is a nique, constitutively secreted…
Description: The biological functions of IL-12 are mediated through specific receptors on T and NK cells. To date, two IL-12 receptor subunits have been identified in mouse and humans. These receptor subunits are members of the cytokine receptor superfamily. Their cytoplasmic regions contain the box1 and box2 motifs that exist in other cytokine…
Description: Interleukin-13 (IL-13) was first described as a protein product, designated P600, encoded by an RNA produced by activated mouse Th2 cells . More recently, the cDNA cloning of the human homologue of P600, human IL-13, has been reported . Human IL-13 is a nonglycosylated protein of 132 amino acids with a molecular weight of 12000Da. The…
Description: IL-13 is an immunoregulatory cytokine secreted predominantly by acvated T cells that exerts its effects mainly on B cells and monocytes.In B cells, IL-13 enhances survival and proliferation, and stimulates immunoglobulin heavy chain class switching to IgE and IgG4. IL-13 is a key mediator of allergic inflammation and has been…
Description: Human IL-22 ELISA kit contains all the necessary reagents required for performing quantitative measurement of Human IL-22 levels from samples including serum, plasma, culture medium or other biological fluids in a sandwich ELISA format.
Description: IL-15 (Interleukin-15) is found in conditioned medium of a monkey kidney epithelial cell line, CV-1/EBNA. It is a glycoprotein of 14-15 kDa. Human IL-15 has been cloned from a human stromal cell line, IMTLH. Stromal cell line IL-15 has been shown to be produced by human fetal astrocytes and microglia in response to IL-1β or IFN-γ and…
Description: Interleukin 21 (IL-21), is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. IL-21 elicits its effects on immune cells by…
Description:Assay Range:20-3200 pg/ml Detection Target:IL-16 Quantity:1 x 96 Sample Type:Sensitivity:<20 pg/ml
Description: Interleukin 17 (IL-17; also known as IL-17A) is a 30 - 35 kDa variably glycosylated homodimeric protein that belongs to a unique family of cysteine-knot related proteins. Its sequence was originally isolated from an activated rodent hybridoma and termed CTLA-8 . It is synthesized as a 155 amino acid (aa) precursor that contains a 23…
Description: Interleukin 18 (IL-18) is a 18 kDa novel cytokine which is identified as a costimulatory factor for production of interferon-γ (IFN- γ ) in response to toxic shock. It shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24 kDa molecule without a signal peptide and must be cleaved to produce an active…
Description: IL-18 binding protein (IL-18BP) is a circulating antagonist of the proinflammatory Th1 cytokine IL-18. IL-18BP belongs to a growing family of soluble inding proteins (osteoprotegerin and cytokine-like actor-1), which are not variants of their cell bound eceptors. Its major splice variant IL-18BPa is a nique, constitutively secreted…
