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Specification:100ul/200ul/1ml Description:
Alpha Synuclein is implicated in the regulation of dopamine release and transport. It is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). In the nervous system, alpha Synuclein is primarily located at presynaptic…
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Specification:100ul/200ul/1ml Description:
STAT1 is known to associate with the transcription factors p48, Sp1, and p300. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family. STAT1 alpha and STAT1 beta isoforms arise by alternative splicing of a single gene. The only difference…
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Specification:100ul/200ul/1ml Description:
Specific functions of the various members of the STAT family are poorly understood. STAT1 and STAT2 form heterodimers that function as more potent inducers of transcription than the STAT1 homodimer. The unique acidic domain of the carboxy-terminal region of STAT2 may interact with cAMP-response-element…
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Specification:100ul/200ul/1ml Description:
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to…
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Specification:100ul/200ul/1ml Description:
Survivin is an anti-apoptotic protein, expressed in the G2/M cell cycle phase. At the onset of mitosis, survivin associates with microtubules of the mitotic spindle in a specific and saturable reaction that is regulated by microtubule dynamics. Disruption of survivin-microtubule interactions results in…
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Specification:100ul/200ul/1ml Description:
The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, but also denotes the human gene encoding it.
The gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein-coupled receptor family member, is mediated by G…
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Specification:100ul/200ul/1ml Description:
Alpha 1-antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily.
It inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation.…
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Specification:100ul/200ul/1ml Description:
Alpha 1-Antitrypsin or α1-antitrypsin (A1AT) is a protease inhibitor belonging to the serpin superfamily. It is generally known as serum trypsin inhibitor. Alpha 1-antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it inhibits a wide variety of proteases.It protects tissues…