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Specification:100ul/200ul/1ml Description:
Tissue Inhibitor of Metalloproteinases 4 (TIMP4) was identified by molecular cloning. TIMP4 shows 37 % amino acid identity with TIMP1 and 51 % homology with TIMP2 and TIMP3. TIMP4 is secreted extracellularly, predominantly in heart and brain tissue. It may function in a tissue specific fashion in…
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Description:
Amylin, or Islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio).
Amylin functions as part of the endocrine pancreas and contributes to glycemic control. The peptide is secreted from the pancreas into the blood circulation…
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Description:
Adipose differentiation-related protein, also known as ADFP or adipophilin, is a protein which in humans is encoded by the ADFP gene.
Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the…
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Description:
The Aryl hydrocarbon receptor (AhR or AHR) is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the chaperones dissociate…
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Specification:100ul/200ul/1ml Description:
Apoptosis inducing factor is a flavoprotein.
Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing DNA fragmentation and chromatin condensation. It also acts as an NADH oxidase. Another AIF function is to…
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Specification:100ul/200ul/1ml Description:
Adenylate kinases 1-5 (AK 1-5) are a set of enzymes that regulate intracellular adenine nucleotide levels. AK influences metabolic signals and promotes intracellular phosphoryl transfer by catalyzing phosphate group exchange between adenine nucleotides. Inherited mutations lead to AK deficiencies in…
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Specification:100ul/200ul/1ml Description:
ALK tyrosine kinase receptor is an enzyme that in humans is encoded by the ALK gene.
The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the…
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Specification:100ul/200ul/1ml Description:
Alpha-methylacyl-CoA racemase, also known as AMACR, is a protein which in humans is encoded by the AMACR gene.
Several studies have suggested that AMACR can be used as a prostate cancer biomarker.
It can cause mental impairment,confusion, learning difficulties and liver damage. It can be treated by…