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Specification:100ul/200ul/1ml Description:
Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration.
SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (…
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Description:
SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors which participate in the control of cholesterol homeostasis. SREBP proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol. Upon…
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Specification:100ul/200ul/1ml Description:
This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that…
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Specification:100ul/200ul/1ml Description:
A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules…
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Specification:100ul/200ul/1ml Description:
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in…
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Specification:100ul/200ul/1ml Description:
A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein…
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Specification:100ul/200ul/1ml Description:
A heterodimeric protein, associated with the membrane skeleton, which promotes the binding of spectrin to actin in a calcium/calmodulin dependent manner. The protein is composed of two similar sub-units, a-adducin ( 103kd) and b-adducin (97kd) which together form higher order structures (dimers &…
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Description:
Adrenocorticotropic hormone (ACTH), also known as 'corticotropin', is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with corticotropin-releasing hormone from the…