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Specification:96testDescription:
Telomerase, a eukaryotic ribonucleoprotein (RNP) complex, contains both an essential RNA and a protein reverse transcriptase subunit. It helps to stabilize telomere length in human stem cells and reproductive cells and cancer cells by adding TTAGGG repeats onto the telomeres using its intrinsic RNA as a template…
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Description:
The TGF-β family is part of a superfamily of proteins known as the transforming growth factor beta superfamily, which includes inhibins, activin, anti-müllerian hormone, bone morphogenetic protein, decapentaplegic and Vg-1. TGF-beta controls proliferation, cellular differentiation, and other functions in most cells. It plays a role in…
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Description:
Tenascin, also known as hexabrachion and cytotactin, is an extracellular matrix protein with a spatially and temporally restricted tissue distribution. It is a hexameric, multidomain protein with disulfide linked subunits of 190 to 240 kD, originally characterized as 'myotendinous antigen.' In the embryo it is present in dense…
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Description:
TGF-β exists in at least five isoforms, known as TGF-β1, TGF-β2, TGF-β3, TGF-β4, TGF-β5. Their amino acid sequences display homologies on the order of 70-80%. The various TGF-β isotypes share many biological activities and their actions on cells are qualitatively similar in most cases although there are a few examples of distinct…
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Description:
The transmembrane protein Tissue factor (TF) is the physiologic trigger of coagulation in normal hemostasis. TF binds and allosterically activates factor VII. The TF-VIIa complex cleaves factor IX and X, leading to thrombin generation . Inducible expression of TF in a variety of pathological conditions, including gram-negative sepsis…
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Description:
Tissue Factor Pathway Inhibitor (TFPI) circulates in plasma as a complex with LDL>HDL>>VLDV. In plasma, TFPI is found in several forms: one at 36,000 kD, one at 43,000 kD, and the various truncated forms. This size heterogeneity appears in part to be the result of the formation of mixed disulfide complexes between TFPI and…
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Specification:96testDescription:
Thyroglobulin (TG)is a water soluble glycoprotein that is involved in the storage and synthesis of thyroid hormones. The thyroid microsomal antigen has been shown to be the enzyme thyroid peroxidase (TPO). Antibodies to thyroglobulin and or microsomal antigen are present in most patients with goitrous thyroiditis (…
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Specification:96testDescription:
TheTGF-alpha ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-alpha in serum, plasma, cell culture supernatants and urine. This assay employs an antibody specific for human TGF-alpha coated on a 96-well plate. Standards and…
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Description:
Telomerase, a eukaryotic ribonucleoprotein (RNP) complex, contains both an essential RNA and a protein reverse transcriptase subunit. It helps to stabilize telomere length in human stem cells and reproductive cells and cancer cells by adding TTAGGG repeats onto the telomeres using its intrinsic RNA as a template for reverse…
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Description:
The thrombospondins (TSP) are a family of multifunctional proteins. The family consists of thrombospondins 1-5 and can be divided into 2 subgroups: A, which contains TSP-1 and -2, and B, which contains TSP-3, -4 and -5 (also designated cartilage oligomeric protein or COMP). TSP-1 and -2 are homotrimers, consisting of three identical…