-
Specification:100ul/200ul/1ml Description:
The ASPP family members ASPP1, ASPP2 (encoded by PPP1R13B and TP53BP2, respectively), act as potent activators of p53. A third member of the family, iASPP, has an inhibitory effect on apoptosis. The three members of ASPP family all bind p53 via their C-terminus, which contains a proline-rich region, four…
-
Description:
BRCA1 (breast cancer 1, early onset) is a human tumor suppressor gene, which produces a protein, called breast cancer type 1 susceptibility protein.
BRCA1 is expressed in the cells of breast and other tissue, where it helps repair damaged DNA, and destroy the cell when DNA can't be repaired. If BRCA1 itself is damaged, the damaged…
-
Description:
Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene.ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling…
-
Specification:100ul/200ul/1ml Description:
Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of C. elegans CED-4 gene.APAF-1 and CED-4 homologs have been found in all currently sequenced animal genomes.
This gene encodes a cytoplasmic protein that forms one the central hubs in the apoptosis regulatory network. This…
-
Specification:100ul/200ul/1ml Description:
Angiopoietin-related protein 4 is a protein that in humans is encoded by the ANGPTL4 gene.
This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial…
-
Specification:100ul/200ul/1ml Description:
Trans-acting T-cell-specific transcription factor GATA-3 is a protein that in humans is encoded by the GATA3 gene.
GATA-3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in…
-
Specification:100ul/200ul/1ml Description:
Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucosylceramide.
It is classified under EC 2.4.1.80.
It is inhibited by miglustat.
-
Specification:100ul/200ul/1ml Description:
Granulocyte colony-stimulating factor (G-CSF or GCSF) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to release them…
Specification:100ul/200ul/1ml Description: The ASPP family members ASPP1, ASPP2 (encoded by PPP1R13B and TP53BP2, respectively), act as potent activators of p53. A third member of the family, iASPP, has an inhibitory effect on apoptosis. The three members of ASPP family all bind p53 via their C-terminus, which contains a proline-rich region, four…
Description: BRCA1 (breast cancer 1, early onset) is a human tumor suppressor gene, which produces a protein, called breast cancer type 1 susceptibility protein. BRCA1 is expressed in the cells of breast and other tissue, where it helps repair damaged DNA, and destroy the cell when DNA can't be repaired. If BRCA1 itself is damaged, the damaged…
Description: Activin receptor type-2A is a protein that in humans is encoded by the ACVR2A gene.ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling…
Specification:100ul/200ul/1ml Description: Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of C. elegans CED-4 gene.APAF-1 and CED-4 homologs have been found in all currently sequenced animal genomes. This gene encodes a cytoplasmic protein that forms one the central hubs in the apoptosis regulatory network. This…
Specification:100ul/200ul/1ml Description: Angiopoietin-related protein 4 is a protein that in humans is encoded by the ANGPTL4 gene. This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial…
Specification:100ul/200ul/1ml Description: Trans-acting T-cell-specific transcription factor GATA-3 is a protein that in humans is encoded by the GATA3 gene. GATA-3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in…
Specification:100ul/200ul/1ml Description: Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucosylceramide. It is classified under EC 2.4.1.80. It is inhibited by miglustat.
Specification:100ul/200ul/1ml Description: Granulocyte colony-stimulating factor (G-CSF or GCSF) is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to release them…
