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Specification:100ul/200ul/1ml Description:
CD274 (Cluster of Differentiation 274) also known as PD-L1 (Programmed Death Ligand-1) or B7-H1 is a protein which in humans is encoded by the CD274 gene.
It appears that upregulation of B7-H1 is a mechanism that cancers can employ to evade the host immune system.
B7-H1 acts as a positive costimulatory…
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Specification:100ul/200ul/1ml Description:
B7-H4, also known as B7x and B7S1, is a member of the B7 family of immune costimulatory proteins. Mature B7-H4 is a 50 kDa - 80 kDa glycosylated molecule with a 28 kDa protein core. Partial sensitivity to cleavage by PI-PLC suggests a possible GPI linkage of mouse B7-H4 to the cell membrane. The 230 aa…
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Specification:100ul/200ul/1ml Description:
Amyloid beta peptide is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimers disease. This peptide is generated from the beta-amyloid precursor protein (beta APP) in a two-step process. The first step involves cleavage of the extracellular, amino-terminal domain…
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Specification:100ul/200ul/1ml Description:
The Bcl-2 homologous antagonist/killer (BAK) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. It has a relative molecular weight of 23,400 and contain 211-amino acids. Dysregulation of the BAK gene has been implicated in human gastrointestinal cancers,…
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Specification:100ul/200ul/1ml Description:
Useful marker for the investigation of malignancy in breast epithelial cells.
Application Notes:ELISA: Use at a dilution of 1/6400. IHC-Fr: Use at a dilution of 1/400. WB: Use at a dilution of 1/400. Has not been shown to work in IHC-P. Not tested in other applications. Optimal dilutions/concentrations…
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Specification:100ul/200ul/1ml Description:
A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA. They occur in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding…
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Specification:100ul/200ul/1ml Description:
Batroxobin is a serine protease derived from the venom of Bothrops atrox. Its molecular weight is approximately 43,000 g/mol?1.
This thrombin-like proteolytic enzyme splits the 16 Arg-17 Gly bond in the A(alpha)-chain of fibrinogen, releasing fibrinopeptide A and leading to the clot formation through…
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Description:
The Bcl-2–associated X protein, or Bax is a protein of the Bcl-2 gene family. It promotes apoptosis by competing with Bcl-2 proper.
The BAX gene was the first identified pro-apoptotic member of the Bcl-2 protein family.Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH…
Specification:100ul/200ul/1ml Description: CD274 (Cluster of Differentiation 274) also known as PD-L1 (Programmed Death Ligand-1) or B7-H1 is a protein which in humans is encoded by the CD274 gene. It appears that upregulation of B7-H1 is a mechanism that cancers can employ to evade the host immune system. B7-H1 acts as a positive costimulatory…
Specification:100ul/200ul/1ml Description: B7-H4, also known as B7x and B7S1, is a member of the B7 family of immune costimulatory proteins. Mature B7-H4 is a 50 kDa - 80 kDa glycosylated molecule with a 28 kDa protein core. Partial sensitivity to cleavage by PI-PLC suggests a possible GPI linkage of mouse B7-H4 to the cell membrane. The 230 aa…
Specification:100ul/200ul/1ml Description: Amyloid beta peptide is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimers disease. This peptide is generated from the beta-amyloid precursor protein (beta APP) in a two-step process. The first step involves cleavage of the extracellular, amino-terminal domain…
Specification:100ul/200ul/1ml Description: The Bcl-2 homologous antagonist/killer (BAK) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. It has a relative molecular weight of 23,400 and contain 211-amino acids. Dysregulation of the BAK gene has been implicated in human gastrointestinal cancers,…
Specification:100ul/200ul/1ml Description: Useful marker for the investigation of malignancy in breast epithelial cells. Application Notes:ELISA: Use at a dilution of 1/6400. IHC-Fr: Use at a dilution of 1/400. WB: Use at a dilution of 1/400. Has not been shown to work in IHC-P. Not tested in other applications. Optimal dilutions/concentrations…
Specification:100ul/200ul/1ml Description: A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA. They occur in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding…
Specification:100ul/200ul/1ml Description: Batroxobin is a serine protease derived from the venom of Bothrops atrox. Its molecular weight is approximately 43,000 g/mol?1. This thrombin-like proteolytic enzyme splits the 16 Arg-17 Gly bond in the A(alpha)-chain of fibrinogen, releasing fibrinopeptide A and leading to the clot formation through…
Description: The Bcl-2–associated X protein, or Bax is a protein of the Bcl-2 gene family. It promotes apoptosis by competing with Bcl-2 proper. The BAX gene was the first identified pro-apoptotic member of the Bcl-2 protein family.Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH…
