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Specification:100ul/200ul/1ml Description:
The BH3 interacting domain death agonist, or BID, gene is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero- or homodimers.…
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Specification:100ul/200ul/1ml Description:
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one ofwhich was initially identified as a MYC-interacting protein with features of a tumorsuppressor. Isoforms that are expressed in the central nervous system may be involvedin synaptic vesicle endocytosis and may interact with…
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Specification:100ul/200ul/1ml Description:
Bim, Bcl2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in…
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Specification:100ul/200ul/1ml Description:
53BP2/ASPP2 plays a central role in regulation of apoptosis and cell growth via its interactions. It regulates p53 by enhancing the DNA binding and transactivation function of p53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby…
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Description:
Beclin-1 is a protein that in humans is encoded by the BECN1 gene.
Beclin-1 is also known as autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy.
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Specification:100ul/200ul/1ml Description:
Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins.
BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor…
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Description:
Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene.
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic…
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Specification:100ul/200ul/1ml Description:
TFF3 belongs to a unique family of abundant GI3 peptides with a distinct 3-loop structure formed by a highly conserved motif of cysteine disulfide bonds, which confer them with remarkable luminal stability . They are mainly synthesized and secreted by mucin-secreting epithelial cells lining the…