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Specification:100ul/200ul/1ml Description:
Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein that in humans is encoded by the TRADD gene.
TRADD is an adaptor protein.
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death…
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Specification:100ul/200ul/1ml Description:
The Trk family of tyrosine protein kinase receptors is responsible for mediating the trophic effects of the NGF family of neurotrophins. TrkC is mainly expressed in nervous tissue and is a functional receptor for neurotrophin 3 (NT3). Although it is primarily expressed in neural lineages, expression can…
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Specification:100ul/200ul/1ml Description:
The induction of the various cellular responses mediated by tumor necrosis factor is initiated by its interaction with the TNFR1 and TNFR2 cell surface receptors. TRAF2 interacts with the cytoplasmic domain of TNFR2. TRAF2 is a common signal transducer for TNFR2 and CD40 that mediates activation of NF…
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Specification:100ul/200ul/1ml Description:
Neurotrophins activate tyrosine kinase receptors of the Trk family (TrkA, TrkB and TrkC) and they all share a common low affinity receptor (p75NTR or p75). Although p75NTR does not appear to directly transduce NGF signals, this receptor appears to increase the responsiveness of the trk receptors and plays…
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Specification:100ul/200ul/1ml Description:
The protein encoded by TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor…
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Specification:100ul/200ul/1ml Description:
Apoptosis or programmed cell death is induced in cells by a group of death domain containing receptors. Binding of ligand to these receptors sends signals that activate members of the caspase family of proteases. The signals ultimately cause degradation of chromosomal DNA by activating DNase. TRAIL (TNF…
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Specification:100ul/200ul/1ml Description:
Transthyretin (TTR) is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol. This is how transthyretin gained its name, transports thyroxine and retinol.
TTR was originally called prealbumin because it ran faster than albumins on electrophoresis gels.
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Description:
TRF1 (Telomere Repeat-Binding Factor 1), which is also known as TERF1, plays a role in the negative regulation of telomere length. It binds to the telomeric double-stranded TTAGGG repeat, and is a component of the shelterin complex, also known as the telosome. Shelterin associates with, and protects, telomere ends. In the absence of…