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Specification:100ul/200ul/1ml Description:
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and…
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Specification:100ul/200ul/1ml Description:
Tyrosinase is a copper containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. It is thought to catalyze the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
A mutant allele of TYR…
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Specification:100ul/200ul/1ml Description:
SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1, SgIGSF, or IGSF4, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily…
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Specification:100ul/200ul/1ml Description:
The Trk proto-oncogene family contains four members, TrkA, TrkB, TrkC, and TrkE, which are variably expressed throughout the central and peripheral nervous systems. TrkA binds to nerve growth factor (NGF) and autophosphorylates on tyrosine residues (Tyr490, Tyr674, Tyr675, Tyr751 and Tyr785) to activate…
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Specification:100ul/200ul/1ml Description:
TTF1 is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.
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Specification:100ul/200ul/1ml Description:
Transcription termination factor 2 (TTF2) is responsible for the mitotic suppression of transcriptional elongation. It is a member of the SWI2/SNF2 protien family which is involved in altering protein/DNA interactions. TTF2 has been shown to have RNA polymerase II termination activity and dsDNA-dependent…
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Specification:100ul/200ul/1ml Description:
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin…
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Specification:100ul/200ul/1ml Description:
Cyclin-dependent kinase 4 is part of the cyclin-dependent kinase family.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex…
Specification:100ul/200ul/1ml Description: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and…
Specification:100ul/200ul/1ml Description: Tyrosinase is a copper containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. It is thought to catalyze the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. A mutant allele of TYR…
Specification:100ul/200ul/1ml Description: SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1, SgIGSF, or IGSF4, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily…
Specification:100ul/200ul/1ml Description: The Trk proto-oncogene family contains four members, TrkA, TrkB, TrkC, and TrkE, which are variably expressed throughout the central and peripheral nervous systems. TrkA binds to nerve growth factor (NGF) and autophosphorylates on tyrosine residues (Tyr490, Tyr674, Tyr675, Tyr751 and Tyr785) to activate…
Specification:100ul/200ul/1ml Description: TTF1 is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.
Specification:100ul/200ul/1ml Description: Transcription termination factor 2 (TTF2) is responsible for the mitotic suppression of transcriptional elongation. It is a member of the SWI2/SNF2 protien family which is involved in altering protein/DNA interactions. TTF2 has been shown to have RNA polymerase II termination activity and dsDNA-dependent…
Specification:100ul/200ul/1ml Description: The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin…
Specification:100ul/200ul/1ml Description: Cyclin-dependent kinase 4 is part of the cyclin-dependent kinase family. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex…
