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Specification:100ul/200ul/1ml Description:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is…
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Specification:100ul/200ul/1ml Description:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through…
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Specification:100ul/200ul/1ml Description:
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and…
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Specification:100ul/200ul/1ml Description:
The Myelin P0 protein (MPZ) creates an extracellular membrane face to guide the wrapping process for ultimately compacting adjacent lamellae. MPZ is a single-pass type I membrane protein only found in peripheral nervous system Schwann cells. Defects in MPZ are the cause of Charcot-Marie-Tooth disease, an…
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Specification:100ul/200ul/1ml Description:
Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized…
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Specification:0.1ml/0.2mlDescription:
S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2…
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Specification:0.1ml/0.2mlDescription:
Semaphorin 6A is cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Semaphorin 6A is required for normal granule cell migration in the developing cerebellum. Semaphorin 6A promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the…
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Specification:0.2ml/200μg 1ml/1mg