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Description:
The largest known protein variant (DMBT1/8kb.2) comprises 2413 amino acids and has a calculated molecular weight of 265 kDa. Probably due to glycosylation the molecular weight of the purified protein is approximately 340 kDa. The smallest known variant (DMBT1/6kb.1), which lacks several SRCR domains and SIDs, comprises 1785 amino…
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Specification:100ul/200ul/1mlDescription:
The DNMT-1 is one of the enzymes responsible for methylation. Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk…
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Specification:100ul/200ul/1mlDescription:
Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA…
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Specification:100ul/200ul/1mlDescription:
Excitatory Amino Acid Transporters (EAAT), formerly known as Glutamate transporters, belong to the family of neurotransmitter transporters. They serve to terminate the excitatory neurotransmitter signal by removal (uptake) of glutamate from the neuronal synapse into Glia cells.
In details, the EAATs are…
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Specification:100ul/200ul/1mlDescription:
Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are…
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Description:
This protein protein interaction antibody pair set comes with two antibodies to detect the protein-protein interaction, one against the DVL1 protein, and the other against the CSNK2A1 protein for use in in situ Proximity Ligation Assay .
Store reagents of the antibody pair set at -20 C or lower. Please aliquot to avoid repeated freeze…
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Specification:100ul/200ul/1mlDescription:
Dynamin 2, also known as DNM2, is a human gene.Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are
associated with microtubules. They have been…
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Specification:100ul/200ul/1mlDescription:
Dysbindin, also known as dystrobrevin-binding protein 1 that contains acoiled-coil. Dysbindin upregulates expression of the pre-synaptic proteins SNAP25 and synapsin I, thereby increasing glutamate release and promoting neuronal viability through Akt signaling. It is a component of the biogenesis of…