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Specification:100ul/200ul/1mlDescription:
The inhibitory neurotransmitter, GABA, acts through two ligand gated channels, GABAa and GABAc receptors and GABAb, the latter of which acts through a G protein mechanism. GABAbR1 is one of two G protein coupled receptors for GABAb that acts as a heteromeric assembly with GABAbR2.
Store at -20°C or -80°C.…
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Description:
MDM2 is a nuclear phosphoprotein with an apparent molecular mass of 90 kD that forms a complex with the p53 tumor suppressor protein. Human MDM2 was identified as a homologous product of the 'murine double minute 2' gene (mdm2). The MDM2 gene enhances the tumorigenic potential of cells when it is overexpressed and encodes a putative…
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Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a…
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Specification:100ul/200ul/1ml Description:
The myocyte enhancer factors-2 (MEF-2) family of transcription factors associate with a variety of co-repressors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four distinct family members arise from alternatively splices transcripts, termed MEF-2A, MEF…
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Specification:100ul/200ul/1ml Description:
T4-binding globulin (TBG) is the major thyroid hormone transport protein in man (summarized by Mori et al., 1995 (PubMed 8530630)). Inherited abnormalities in the level of serum TBG have been classified as partial deficiency, complete deficiency, and excess. Patients are euthyroid.
Short term (up to 7…
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Description:
This antibody is specific to a 20 kD protein known as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. This antibody does not cross react with MAGE-1 or tyrosinase protein. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes.
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Description:
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal…
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Specification:100ul/200ul/1ml Description:
The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as…