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Specification:100ul/200ul/1ml Description:
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 19-kDa prohormone processed into PACAP-related peptide (PRP-48), PACAP-27 and PACAP-38. PACAP stimulates adenylate cyclase in pituitary cells, playing pivotal roles as neurotransmitter and neuromodulator. PACAP belongs to the glucagon family…
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Specification:100ul/200ul/1ml Description:
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.
p53 can apparently be…
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Specification:100ul/200ul/1ml Description:
RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58)is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARDdomains, a helicase ATP-binding domain and a helicase C-terminal domain.Predicted molecular weight approximately 107 kD. RIG-1 has an essentialfunction in double-…
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Description:
The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter…
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Specification:100ul/200ul/1ml Description:
p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic…
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Specification:100ul/200ul/1ml Description:
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression (1,2). p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5' oligopyrimidine tract mRNAs . A second isoform, p85 S6…
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Specification:100ul/200ul/1ml Description:
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which interacts with the receptor within extracellular loop-2 to affect transmembrane…
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Specification:100ul/200ul/1ml Description:
Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.
HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes…
Specification:100ul/200ul/1ml Description: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 19-kDa prohormone processed into PACAP-related peptide (PRP-48), PACAP-27 and PACAP-38. PACAP stimulates adenylate cyclase in pituitary cells, playing pivotal roles as neurotransmitter and neuromodulator. PACAP belongs to the glucagon family…
Specification:100ul/200ul/1ml Description: p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. p53 can apparently be…
Specification:100ul/200ul/1ml Description: RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58)is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARDdomains, a helicase ATP-binding domain and a helicase C-terminal domain.Predicted molecular weight approximately 107 kD. RIG-1 has an essentialfunction in double-…
Description: The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter…
Specification:100ul/200ul/1ml Description: p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic…
Specification:100ul/200ul/1ml Description: p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression (1,2). p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5' oligopyrimidine tract mRNAs . A second isoform, p85 S6…
Specification:100ul/200ul/1ml Description: Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which interacts with the receptor within extracellular loop-2 to affect transmembrane…
Specification:100ul/200ul/1ml Description: Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene. HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes…
