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Specification:96TestDescription:
Prostaglandin F2 alpha is involved in a number of physiologic processes. It serves as a potent luteolytic agent in many species, has been implicated as a modulator of intraocular pressure, and may be important in smooth muscle contraction in the uterus and elsewhere. Its effects on cells are mediated through…
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Specification:96TestDescription:
Platelet-activating factor, a compound that reduces inflammation by increasing permeability of blood vessels and contracting various involuntary muscles such as those in airways. It is a phospholipid with a wide range of proinflammatory actions, is immediately degraded and inactivated in vivo by PAF acetylhydrolase…
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Specification:96TestDescription:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase, PMNL collagenase or collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than…
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Specification:96TestDescription:
Neural Cell Adhesion Molecule (NCAM, also the cluster of differentiation CD56) is a homophilic binding glycoprotein expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and…
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Specification:96TestDescription:
Neutrophil elastase is a serine protease in the same family as chymotrypsin and has broad substrate specificity. Secreted by neutrophils during inflammation, it destroys bacteria and host tissue. As with other serine proteases it contains a charge relay system composed of the catalytic triad of histidine, aspartate…
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Specification:96TestDescription:
This kit is a solid phase-phase sandwich enzyme linked immuno sorbent assay (ELISA). Samples, including standards of known target protein concentrations and unknowns are pipetted into these wells. During the first incubation, the target protein antigen and a biotinylated monoclonal antibody specific for target…
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Specification:96TestDescription:
Neopterin (6-[1‘2‘3‘-D-erythro-trihydroxy] propylpterin) is a pyrazinopyrimidine compound derived from guanosine triphosphate (GTP). lt represents an intermediate product in the synthetic pathway of biopterin. Biopterin is an essential co-factor in neurotransmitter synthesis. Tetrahydrobiopterin is the co-factor of…
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Specification:96TestDescription:
Neurokinin A is a member of the tachykinin familiy of neuropeptide neurotransmitters. It is produced from the same preprotachykinin gene as its fellow neuropeptide, substance P. It has various roles roles in the body of humans and other animals. One specific example is mediating contraction of the rat colon.
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Specification:96TestDescription:
Neurokinin B is a tachykinin peptide. Tachykinin peptides are one of the largest family of neuropeptides, found from amphibians to mammals. The tachykinin family is characterized by a common C-terminal sequence, Phe-X-Gly-Leu-Met-NH2, where X is either an Aromatic or an Aliphatic amino acid. The most notable…
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Specification:96TestDescription:
Normetanephrine and metanephrine are physiologically formed from the catecholamines noradrenaline and adrenaline by the enzyme catechol-
O-methyltransferase (COMT). Increased levels of normetanephrine und metanephrine can be found in patients suffering from pheochromocytoma, ganglioneuroma and other neurogenic…