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Description:
Keratinocyte Growth Factor (KGF) is a single chain, heparin-binding, 28 kDa glycoprotein that was originally isolated from media conditioned by the growth of human embryonic lung fibroblasts . Also known as FGF-7 (or fibroblast growth factor 7), it is part of the rapidly-expanding fibroblast growth factor family that currently…
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Description:
Interleukin-31 (IL-31) is a 24kD α-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells1. This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a…
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Description:
IL-31 is a recently identified cytokine made predominantly by CD4+ Th2 cells and its receptor, IL-31R, is expressed by a number of cell types including monocytes, epithelial cells, and T cells.
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Description:
Interleukin (IL)-32 is a recently identified proinflammatory cytokine that is one of the IL-18 inducible genes, and plays an important role in autoimmune and inflammatory diseases. IL-32 can induce cells of the immune system (such as monocytes and macrophages) to secrete tumor necrosis factor-alpha (TNF-α) in addition to chemokines…
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Description:
Through its immunoregulatory properties, IFNα-2a may be effective in a helminthic liver infection and is a promising candidate for clinical application in AE.
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Description:
Circulating antibodies to intra-cellular structures especially to nuclear antigens represent a characteristic feature of Jo-1 ELISA systemic autoimmune diseases. One of those antigens, Jo-1 (Aminoacyl-tRNA Synthetase), was first described in the serum of a myositis patient. A large number of patients with anti-synthetase syndrome…
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Description:
The DAI Legionella IgG/IgA/IgM ELISA test system is designed to detect antibodies to L. pneumophila in human sera. Wells of plastic microwell strips are sensitized by passive absorption with Legionella antigen.
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Description:
KC, also known as CXCL1 or N51, was originally identified in fibroblasts as a PDGF-induced immediate early gene that encodes a secretory protein of approximately 8 kDa. The protein sequence of mouse KC identified it as a member of the alpha (CXC) chemokine family of inflammatory and immunoregulatory cytokines. Besides mitogen-…
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Description:
The Diagnostic Automation Legionella ELISA Test System is an enzyme-linked immunosorbent assay for the qualitative detection of total antibody (IgG/IgM/IgA) to Legionella pneumophila serogroups 1-6 in human sera. This device is for in vitro diagnostic use.
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Description:
Lactoferrin (LF) is a multifunctional iron-binding protein with antimicrobial activities. It is found in milk and other mucosal secretions. Lactoferrin is known to be part of the innate defense against infection and inflammation and also has function in regulation of iron absorption.