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Specification:96TestDescription:
Vascular endothelial growth factor receptor-1 (VEGF R1, also known as Flt-1) was originally discovered through the screening of a human placental cDNA library (1). It is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. VEGF R1 is expressed in two forms via…
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Specification:96TestDescription:
VEGF R2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human VEGF R2 in serum, plasma, cell culture supernatants and urine. This assay employs an antibody specific for human VEGF R2 coated on a 96-well plate. Standards and …
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Specification:96TestDescription:
VEGFR-3 (FLT4) is a receptor tyrosine kinase similar in structure to VEGFR-1 and VEGFR-2 but does not bind VEGF. However, the two known ligands have a high degree of homology to VEGF and are known as VEGF-C and VEGF-D. VEGFR-3 is reported to be found in many tissues including lung, intestine, brain and placenta (…
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Specification:96TestDescription:
Vasoactive intestinal peptide (VIP) is a 28 amino acid residues containing peptide hormone. VIP is produced in many areas of the human body including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain. VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach,…
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Specification:96testDescription:
Macrophage inflammatory protein-2 (MIP-2) was originally identified as a heparin-binding protein secreted by an LPS-stimulated mouse macrophage cell line. MIP-2 was classified as a member of the alpha(CXC) chemokine family of inflammatory and immunoregulatory cytokines .MIP-2 exhibits potent neutrophil chemotactic…
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Specification:96testDescription:
Vitamin B12 is a member of the vitamin B complex. It contains cobalt, and so is also known as cobalamin. It is exclusively synthesised by bacteria and is found primarily in meat, eggs and dairy products. There has been considerable research into proposed plant sources of vitamin B12. Fermented soya products,…
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Description:
Vitamin D is bound in the blood to a binding protein (VDBP) and is metabolized in the liver to 25-OH vitamin D. 25-OH vitamin D has little biological activity, however, it comprises the most abundant of all circulating vitamin D metabolites. Its high affinity for the binding protein (VDBP) makes it the main storage form of vitamin D…
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Description:
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) or vasculotropin, is a homodimeric 34 -42 kDa, heparin-binding glycoprotein with potent angiogenic, mitogenic and vascular permeability-enhancing activities specific for endothelial cells. The most important member is VEGF-A. Other members are…
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Specification:96testDescription:
Studies of ubiquitin cDNAs and genes show 2 unusual gene structural arrangements (Schlesinger and Bond, 1987). The first type of arrangement is the polyubiquitin gene, consisting of tandem repeats of a ubiquitin coding unit, with the number of repeats varying considerably even within species. Presumably…
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Specification:96testDescription:
Calcitonin is a polypeptide hormone of 32 amino acids, with a molecular weight of 3454.93 daltons. Calcitonin is produced in humans primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium (Ca2+), opposing the…