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Description:
Arginine vasopressin (AVP), also known as argipressin, antidiuretic hormone (ADH), or simply as vasopressin, is a nine amino acid peptide hormone that plays a primary role in the regulation of renal water excretion and a secondary role in the regulation of cardiovascular function in mammals.AVP acts on epithelial cells of the urinary…
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Specification:96TestDescription:
A soluble form of Fas-L (sFas-L) is naturally produced by metallo-proteinase-mediated processing. The soluble form resulting from this cleavage was shown to induce apoptosis in susceptible cells. Several lines of evidence suggest that sFas-L may be involved in the pathogenesis of tissue injury. Circulating sFas-L…
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Specification:96TestDescription:
TARC is a protein that was identified by cloning the D3A gene from peripheral blood mononuclear cells (PBMCs) after stimulation with PHA. The only other major source of expression was the thymus. Thus, the protein was named TARC for Thymus and Activation-Regulated Chemokine. TARC is a basic protein with a predicted…
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Specification:96TestDescription:
P-selectin belongs to the selectin family of adhesion molecules. P-selectin acts as a receptor that supports binding of leukocytes to activated platelets and endothelium. P-selectin-mediated adhesive interactions operate in conjunction with cell-cell interactions directed by related molecules and are likely to be…
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Specification:96TestDescription:
Soluble L-Selectin (sL-Selectin) derived from lymphocytes is about 62 kDa, while the fragment derived from neutrophils is 75 - 100 kDa . sL-Selectin retains bioactivity, and at high concentrations can inhibit binding of lymphocytes to endothelium。
The Human sL-Selectin Immunoassay is a 2 hour solid phase ELISA that…
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Description:
Soluble E-selectin (sE-selectin, sCD62E) is present in plasma of healthy individuals and in tissue culture medium of endothelium activated by TNF-alpha, IL-1 or LPS. Enhanced plasma levels of soluble E-selectin have been found in inflammatory, infectious and malignant diseases. Increasing evidence indicates that the expression of the…
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Specification:96TestDescription:
APO-1/Fas (CD95), a member of the TNF/NGF receptor superfamily, is a glycosylated 48kD surface protein containing a single transmembrane region. APO-1 is expressed on a variety of human B and T cell lines, on many different tumor cells and on various normal human tissues . Triggering of APO-1 by its ligand or by…
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Specification:96TestDescription:
Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin. SHBG is produced by the liver cells and is released into the bloodstream. Other sites…
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Specification:96TestDescription:
Intercellular Adhesion Molecule-1 (ICAM-1) is a member of the immunoglobulin supergene family [Rothlein et al., 1988] and functions as a ligand for integrin alphaLbeta2 or Lymphocyte Function-Associated Antigen-1 (LFA-1), a member of the leukocyte integrin family which mediates lymphocyte adhesion.
ICAM-1 is a…
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Specification:96TestDescription:
The sICAM-2 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of soluble Intercellular Adhesion Molecule-2 levels in cell culture supernatants, human serum, plasma, or other body fluids. The ICAM-2 ELISA is for research use only. Not for use in diagnostic or therapeutic procedures.