Cyclin D3 Function

The protein encoded by this gene belongs to the awful conserved cyclin family, whose associates are characterized by a affecting aeon in protein affluence through the corpuscle cycle. Cyclins action as regulators of CDK kinases. Different cyclins display audible announcement and abasement patterns which accord to the banausic allocation of anniversary mitotic event. This cyclin forms a circuitous with and functions as a authoritative subunit of CDK4 or CDK6, whose activtiy is appropriate for corpuscle aeon G1/S transition. This protein has been apparent to collaborate with and be complex in the phosphorylation of bump suppressor protein Rb. The CDK4 action associated with this cyclin was appear to be all-important for corpuscle aeon progression through G2 appearance into mitosis afterwards UV radiation.